Nonlinear Model Predictive Control for Integrated Energy-Efficient Torque-Vectoring and Anti-Roll Moment Distribution

This study applies nonlinear model predictive control (NMPC) to the torque-vectoring (TV) and front-to-total anti-roll moment distribution control of a four-wheel-drive electric vehicle with in-wheel-motors, a brake-by-wire system, and active suspension actuators. The NMPC cost function formulation is based on energy efficiency criteria, and strives to minimize the power losses caused by the longitudinal and lateral tire slips, friction brakes, and electric powertrains, while enhancing the vehicle cornering response in steady-state and transient conditions. The controller is assessed through simulations using an experimentally validated high-fidelity vehicle model, along ramp steer and multiple step steer maneuvers, including and excluding the direct yaw moment and active anti-roll moment distribution actuations. The results show: 1) the substantial enhancement of energy saving and vehicle stabilization performance brought by the integration of the active suspension contribution and TV; 2) the significance of the power loss terms of the NMPC formulation on the results; and 3) the effectiveness of the NMPC with respect to the benchmarking feedback and rule based controllers

On the model-based design of front-to-total anti-roll moment distribution controllers for yaw rate tracking

In passenger cars active suspensions have been traditionally used to enhance comfort through body control, and handling through the reduction of the tyre load variations induced by road irregularities. However, active suspensions can also be designed to track a desired yaw rate profile through the control of the anti-roll moment distribution between the front and rear axles. The effect of the anti-roll moment distribution relates to the nonlinearity of tyre behaviour, which is difficult to capture in the linearised vehicle models normally used for control design. Hence, the tuning of anti-roll moment distribution controllers is usually based on heuristics. This paper includes an analysis of the effect of the lateral load transfer on the lateral axle force and cornering stiffness. A linearised axle force formulation is presented, and compared with a formulation from the literature, based on a quadratic relationship between cornering stiffness and load transfer. Multiple linearised vehicle models for control design are assessed in the frequency domain, and the respective controllers are tuned through optimisation routines. Simulation results from a nonlinear vehicle model are discussed to analyse the performance of the controllers, and show the importance of employing accurate models of the lateral load transfer effect during control design

Irritable bowel syndrome, inflammatory bowel disease and the microbiome

PURPOSE OF REVIEW: The review aims to update the reader on current developments in our understanding of how the gut microbiota impact on inflammatory bowel disease and the irritable bowel syndrome. It will also consider current efforts to modulate the microbiota for therapeutic effect. RECENT FINDINGS: Gene polymorphisms associated with inflammatory bowel disease increasingly suggest that interaction with the microbiota drives pathogenesis. This may be through modulation of the immune response, mucosal permeability or the products of microbial metabolism. Similar findings in irritable bowel syndrome have reinforced the role of gut-specific factors in this ‘functional’ disorder. Metagenomic analysis has identified alterations in pathways and interactions with the ecosystem of the microbiome that may not be recognized by taxonomic description alone, particularly in carbohydrate metabolism. Treatments targeted at the microbial stimulus with antibiotics, probiotics or prebiotics have all progressed in the past year. Studies on the long-term effects of treatment on the microbiome suggest that dietary intervention may be needed for prolonged efficacy. SUMMARY: The microbiome represents ‘the other genome’, and to appreciate its role in health and disease will be as challenging as with our own genome. Intestinal diseases occur at the front line of our interaction with the microbiome and their future treatment will be shaped as we unravel our relationship with it

Investigation of the Enteric Pathogenic Potential of Oral Campylobacter concisus Strains Isolated from Patients with Inflammatory Bowel Disease

BACKGROUND: Campylobacter concisus, a bacterium colonizing the human oral cavity, has been shown to be associated with inflammatory bowel disease (IBD). This study investigated if patients with IBD are colonized with specific oral C. concisus strains that have potential to cause enteric diseases. METHODOLOGY: Seventy oral and enteric C. concisus isolates obtained from eight patients with IBD and six controls were examined for housekeeping genes by multilocus sequence typing (MLST), Caco2 cell invasion by gentamicin-protection-assay, protein analysis by mass spectrometry and SDS-PAGE, and morphology by scanning electron microscopy. The whole genome sequenced C. concisus strain 13826 which was isolated from an individual with bloody diarrhea was included in MLST analysis. PRINCIPAL FINDINGS: MLST analysis showed that 87.5% of individuals whose C. concisus belonged to Cluster I had inflammatory enteric diseases (six IBD and one with bloody diarrhea), which was significantly higher than that in the remaining individuals (28.6%) (P<0.05). Enteric invasive C. concisus (EICC) oral strain was detected in 50% of patients with IBD and none of the controls. All EICC strains were in Cluster 1. The C. concisus strain colonizing intestinal tissues of patient No. 1 was closely related to the oral C. concisus strain from patient No. 6 and had gene recombination with the patient's own oral C. concisus. The oral and intestinal C. concisus strains of patient No. 3 were the same strain. Some individuals were colonized with multiple oral C. concisus strains that have undergone natural recombination. CONCLUSIONS: This study provides the first evidence that patients with IBD are colonized with specific oral C. concisus strains, with some being EICC strains. C. concisus colonizing intestinal tissues of patients with IBD at least in some instances results from an endogenous colonization of the patient's oral C. concisus and that C. concisus strains undergo natural recombination

Machine and actuator design: modeling 3-D fields and forces using the analytical surface charge expressions

Many modern advanced electromagnetic devices, e.g. motors and actuators, use permanent magnets as a source of magnetic fields. The strong and reliable magnetic fields of today’s rare-earth permanent magnets increase their force density. Most of them are based on the interaction between the magnetic field of permanent magnets and current-carrying coils. However, magnetic couplings or electromagnetic vibration isolation systems rely on the strong and position-dependent passive force between permanent magnets instead of an active force resulting from a current. An accurate, noise-free computational description of these interactions is therefore essential for future developments of these high-performance devices. The considered configurations are free-space unbounded problems and do not exhibit structural periodicity. As a three-dimensional magnetic field solution is required, the analytical surface charge method is the model of choice. The expressions for the interaction force between PMs with an (anti-)parallel, perpendicular, and rotated magnetization are derived considering a configuration with two PMs. These could be extended to include various other electromagnetic device structures. Further, the developments in the analytical surface charge expressions of the interaction forces between cuboidal permanent magnets are addressed. Finally, extensions to the surface charge method are proposed, aiming to create a fully 6-DoF permanent magnet interaction model, which can serve as a fast, analytical replacement to the finite element method

Soft-landing control of low-energy solenoid valve actuators

An automotive, fluid-control solenoid valve is composed of an electromagnetic reluctance actuator and a near-constant-force spring. Its motion profile is characterized by short closed-To-open transition times which demand fast switching, while valve lifetime improves by minimizing the impact velocity, i.e. a soft landing. In this paper, a cascaded position-and current-feedback control is designed and implemented on nonlinear, axisymmetric magnetostatic finite element simulations of a low-energy solenoid valve actuator. By applying the cascaded control, actuator performance is improved considerably, as a soft landing, a timely actuation, and an increased energy-efficient device have been obtained

Preview-based techniques for vehicle suspension control: a state-of-the-art review

Automotive suspension systems are key to ride comfort and handling performance enhancement. In the last decades semi-active and active suspension configurations have been the focus of intensive automotive engineering research, and have been implemented by the industry. The recent advances in road profile measurement and estimation systems make road-preview-based suspension control a viable solution for production vehicles. Despite the availability of a significant body of papers on the topic, the literature lacks a comprehensive and up-to-date survey on the variety of proposed techniques for suspension control with road preview, and the comparison of their effectiveness. To cover the gap, this literature review deals with the research conducted over the past decades on the topic of semi-active and active suspension controllers with road preview. The main formulations are reported for each control category, and the respective features are critically analysed, together with the most relevant performance indicators. The paper also discusses the effect of the road preview time on the resulting system performance, and identifies control development trends

Analytical surface charge method for rotated permanent magnets: boundary element method comparison and experimental validation

This paper is concerned with the analytical calculation of the interaction force between two permanent magnets (PMs) under relative rotation by means of the surface charge method, taking into account the non-unity relative permeability of the PMs. This model combines high accuracy and short calculation time. As the considered PM configuration is a free-space, unbounded problem, the results from the surface charge method are compared with its numerical counterpart, the boundary element method. The analytical expressions were validated by means of the measurement results obtained from a 3-D printed test setup.J. R. M. van Dam, J. J. H. Paulides, W. S. P. Robertson, M. Dhaens, E. A. Lomonov